Research
Explore published research, case studies, and presentations from the Enable Medicine team.
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June 29, 2024
Publication
Patient response
Single-cell
Spatial multi-omics
Single-cell spatial multiomics reveals tumor microenvironment vulnerabilities in cancer resistance to immunotherapy
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Cell Reports
June 29, 2024
Publication
Patient response
Single-cell
Spatial multi-omics
Single-cell spatial multiomics reveals tumor microenvironment vulnerabilities in cancer resistance to immunotherapy
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Cell Reports
Spatial multi-omics
Single-cell
single-cell, spatial, multiomics, immunotherapy
January 26, 2024
Publication
Patient response
Mechanisms of action
Single-cell transcriptomics
A single-cell atlas of IL-23 inhibition in cutaneous psoriasis distinguishes clinical response
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Science Immunology
January 26, 2024
Publication
Patient response
Mechanisms of action
Single-cell transcriptomics
A single-cell atlas of IL-23 inhibition in cutaneous psoriasis distinguishes clinical response
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Science Immunology
Machine learning
Single-cell transcriptomics
CODEX
Visium
IL-23 inhibition response
November 1, 2023
Publication
Atherosclerotic plaque
Tissue microenvironment
Spatial multi-omics
Combined Near Infrared Photoacoustic Imaging and Ultrasound
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Elsevier
November 1, 2023
Publication
Atherosclerotic plaque
Tissue microenvironment
Spatial multi-omics
Combined Near Infrared Photoacoustic Imaging and Ultrasound
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Elsevier
Spatial proteomics
Spatial transcriptomics
Multiplexed imaging
November 1, 2023
Poster
Data abstraction
Open source
Spatial-omics
emObject: An open-source domain-specific data abstraction for spatial omics
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Society for Immunotherapy of Cancer
November 1, 2023
Poster
Data abstraction
Open source
Spatial-omics
emObject: An open-source domain-specific data abstraction for spatial omics
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Society for Immunotherapy of Cancer
Spatial-omics
Spatial analysis
Visium
Spatial-omics abstraction
November 1, 2023
Poster
Tissue structure segmentation
Diabetic kidney disease (DKD)
Spatial-omics
Characterizing Tissue Structures from Spatial Omics with Spatial Cellular Graph Partition
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Society for Immunotherapy of Cancer
November 1, 2023
Poster
Tissue structure segmentation
Diabetic kidney disease (DKD)
Spatial-omics
Characterizing Tissue Structures from Spatial Omics with Spatial Cellular Graph Partition
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Society for Immunotherapy of Cancer
Spatial-omics
Spatial Cellular Graph Partition (SCGP)
Tissue structure characterization
November 1, 2023
Poster
Cell phenotyping
Polarity
Spatial proteomics
PEPSI: Polarity measurements from spatial proteomics imaging suggest immune cell engagement
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Society for Immunotherapy of Cancer
November 1, 2023
Poster
Cell phenotyping
Polarity
Spatial proteomics
PEPSI: Polarity measurements from spatial proteomics imaging suggest immune cell engagement
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Society for Immunotherapy of Cancer
Spatial proteomics
PEPSI
Immunofluorescence imaging
Machine learning
spatial proteomics
November 1, 2023
Poster
Head-and-neck cancer
Cell morphology
Multiplexed imaging
Quantitative cell morphology featurization in multiplexed immunofluorescence images reveals tumor subtypes in cancer microenvironments
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Society for Immunotherapy of Cancer
November 1, 2023
Poster
Head-and-neck cancer
Cell morphology
Multiplexed imaging
Quantitative cell morphology featurization in multiplexed immunofluorescence images reveals tumor subtypes in cancer microenvironments
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Society for Immunotherapy of Cancer
Multiplexed imaging
Single-cell spatial phenotyping
CODEX
Tumor cell morphology
November 1, 2023
Poster
Computational pipeline
Biomarkers
Spatial transcriptomics
An end-to-end Visium spatial transcriptomics computational pipeline for generating low-code interactive reports of spatial insights
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American Association for Cancer Research
November 1, 2023
Poster
Computational pipeline
Biomarkers
Spatial transcriptomics
An end-to-end Visium spatial transcriptomics computational pipeline for generating low-code interactive reports of spatial insights
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American Association for Cancer Research
Spatial transcriptomics
Visium
10X Genomics
Spatial transcriptomics computational pipeline
November 1, 2023
Poster
Non-small cell lung cancer (NSCLC)
Tumor microenvironment (TME)
Spatial-omics
Integrative Spatial Multi-Omics Analysis of Nsclc Tumor Microenvironment Identifies Key Features Associated With Response to Immune Checkpoint Inhibitor Therapy
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Society for Immunotherapy of Cancer
November 1, 2023
Poster
Non-small cell lung cancer (NSCLC)
Tumor microenvironment (TME)
Spatial-omics
Integrative Spatial Multi-Omics Analysis of Nsclc Tumor Microenvironment Identifies Key Features Associated With Response to Immune Checkpoint Inhibitor Therapy
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Society for Immunotherapy of Cancer
Spatial-omics
Spatial proteomics
CODEX
Spatial analysis NSCLC
November 1, 2023
Poster
Biomarkers
Spatial cellular profiling
Spatial proteomics
From images to insights - Deep spatial profiling reveals disease and treatment biomarkers
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Society for Immunotherapy of Cancer
November 1, 2023
Poster
Biomarkers
Spatial cellular profiling
Spatial proteomics
From images to insights - Deep spatial profiling reveals disease and treatment biomarkers
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Society for Immunotherapy of Cancer
Single cell omics
Spatial proteomics
Multiplexed imaging
SPACE-GM
Deep spatial profiling