Research
Explore published research, case studies, and presentations from the Enable Medicine team.
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November 1, 2023
Poster
Image analysis
Tissue detection
Machine learning
A machine learning toolkit for automated processing of multiplexed immunofluorescence images
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Society for Immunotherapy of Cancer
November 1, 2023
Poster
Image analysis
Tissue detection
Machine learning
A machine learning toolkit for automated processing of multiplexed immunofluorescence images
READ NOW
Society for Immunotherapy of Cancer
Multiplexed imaging
Machine learning
Machine learning mIF
October 20, 2023
Publication
Mechanisms of action
Autoimmune
Multiplexed imaging
Microenvironmental network of clonal CXCL13+CD4+ T cells and regulatory T cells in pemphigus chronic blisters
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Enable Medicine
October 20, 2023
Publication
Mechanisms of action
Autoimmune
Multiplexed imaging
Microenvironmental network of clonal CXCL13+CD4+ T cells and regulatory T cells in pemphigus chronic blisters
READ NOW
Enable Medicine
Spatial transcriptomics
Multiplexed imaging
Immunofluorescence imaging
CODEX
Single-cell RNA sequencing
Cell microenvironmental network
September 8, 2023
Case study
Patient stratification
Cell microenvironment
Geometric deep learning
SPACE-GM: Decoding Disease-Relevant Microenvironments Using Geometric Deep-Learning
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Enable Medicine
September 8, 2023
Case study
Patient stratification
Cell microenvironment
Geometric deep learning
SPACE-GM: Decoding Disease-Relevant Microenvironments Using Geometric Deep-Learning
READ NOW
Enable Medicine
Spatial proteomics
Multiplexed imaging
High-plex imaging
SPACE-GM
Geometric deep learning
Deep-learning framework
August 21, 2023
Publication
SARS-CoV-2
Tissue microenvironment
Spatial multi-omics
A robust platform for integrative spatial multi-omics analysis to map immune reponses to SARS-CoV-2 infection in lung tissue
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Wiley
August 21, 2023
Publication
SARS-CoV-2
Tissue microenvironment
Spatial multi-omics
A robust platform for integrative spatial multi-omics analysis to map immune reponses to SARS-CoV-2 infection in lung tissue
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Wiley
Multiplexed imaging
Spatial proteomics
Spatial transcriptomics
CODEX
RNAscope
Immune response mapping
June 6, 2023
Publication
Biomarkers
Tissue microenvironment
In silico multiplexed imaging
7-UP: generating in silico CODEX from a small set of immunofluorescence markers
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PNAS Nexus
June 6, 2023
Publication
Biomarkers
Tissue microenvironment
In silico multiplexed imaging
7-UP: generating in silico CODEX from a small set of immunofluorescence markers
READ NOW
PNAS Nexus
Multiplexed imaging
In silico multiplexed imaging
7-UP
In silico CODEX
April 14, 2023
Poster
Immuno-oncology
Tumor microenvironment (TME)
Single-cell spatial phenotyping
Design and validation of ultrahigh-plex discovery panels for immuno-oncology and oncology
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American Association for Cancer Research
April 14, 2023
Poster
Immuno-oncology
Tumor microenvironment (TME)
Single-cell spatial phenotyping
Design and validation of ultrahigh-plex discovery panels for immuno-oncology and oncology
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American Association for Cancer Research
Single-cell spatial phenotyping
PhenoCycler
Ultrahigh-plex
April 14, 2023
Poster
Non-small cell lung cancer (NSCLC)
Immunotherapy
Spatial transcriptomics
Immune profiling of immunotherapy and adjuvant chemotherapy pretreatment of NSCLC tissues by CODEX
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American Association for Cancer Research
April 14, 2023
Poster
Non-small cell lung cancer (NSCLC)
Immunotherapy
Spatial transcriptomics
Immune profiling of immunotherapy and adjuvant chemotherapy pretreatment of NSCLC tissues by CODEX
READ NOW
American Association for Cancer Research
Multiplexed imaging
Spatial transcriptomics
CODEX
CODEX immune profiling
April 14, 2023
Poster
Biomarkers
Breast cancer
Multiplexed imaging
Precise spatial multiplexing of protein biomarkers for immune profiling in tissue samples with ChipCytometry™
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American Association for Cancer Research
April 14, 2023
Poster
Biomarkers
Breast cancer
Multiplexed imaging
Precise spatial multiplexing of protein biomarkers for immune profiling in tissue samples with ChipCytometry™
READ NOW
American Association for Cancer Research
Multiplexed imaging
Spatial proteomics
ChipCytometry
ChipCytometry multiplex
April 14, 2023
Poster
Non-small cell lung cancer (NSCLC)
Mechanisms of action
Single cell omics
Single-cell spatial proteomic analysis of the tumor microenvironment in naive NSCLC samples with immunotherapy treatment and response data
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American Association for Cancer Research
April 14, 2023
Poster
Non-small cell lung cancer (NSCLC)
Mechanisms of action
Single cell omics
Single-cell spatial proteomic analysis of the tumor microenvironment in naive NSCLC samples with immunotherapy treatment and response data
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American Association for Cancer Research
Single cell omics
High-plex imaging
Multiplexed imaging
Single-cell analysis NSCLC
April 13, 2023
Publication
Diabetic kidney disease (DKD)
Mechanisms of action
Spatial proteomics
Spatial Proteomics of Human Diabetic Kidney Disease
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bioRxiv
April 13, 2023
Publication
Diabetic kidney disease (DKD)
Mechanisms of action
Spatial proteomics
Spatial Proteomics of Human Diabetic Kidney Disease
READ NOW
bioRxiv
Spatial proteomics
Multiplexed imaging
Spatial proteomics DKD